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DNA of Erythroid Origin Is Present in Human Plasma and Informs the Types of Anemia

7 Aug 2017

Abstract excerpt

BACKGROUND: There is much interest in the tissue of origin of circulating DNA in plasma. Data generated using DNA methylation markers have suggested that hematopoietic cells of white cell lineages are important contributors to the circulating DNA pool. However, it is not known whether cells of the erythroid lineage would also release DNA into the plasma. METHODS: Using high-resolution methylation profiles of...

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PMID: 28784691
DOI: 10.1373/clinchem.2017.272401

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