Article
U2AF1 and EZH2 mutations are associated with nonimmune hemolytic anemia in myelodysplastic syndromes.
Blood advances - 10 Jan 2023
Komrokji Rami, Aguirre Luis E, Al Ali Najla, Hussaini Mohamad, Sallman David, Rollison Dana, Padron Eric
Abstract excerpt
Hemolysis is a well-recognized but poorly characterized phenomenon in a subset of patients with myelodysplastic syndromes (MDS). Its pathobiological basis seems to underpin a nonimmune etiology whose clinical significance has not been adequately characterized. Hemolysis in MDS is often attributed to either ineffective intramedullary erythropoiesis or acquired hemoglobinopathies and red blood cell (RBC) membrane...
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