Article
Transcriptome-Wide Analysis Identifies Novel Associations With Blood Pressure.
Hypertension (Dallas, Tex. : 1979) - 1 Oct 2017
Zeller Tanja, Schurmann Claudia, Schramm Katharina, Müller Christian, Kwon Soonil, Wild Philipp S, Teumer Alexander, Herrington David, Schillert Arne, Iacoviello Licia, Kratzer Adelheid, Jagodzinski Annika, Karakas Mahir, Ding Jingzhong, Neumann Johannes T, Kuulasmaa Kari, Gieger Christian, Kacprowski Tim, Schnabel Renate B, Roden Michael, Wahl Simone, Rotter Jerome I, Ojeda Francisco, Carstensen-Kirberg Maren, Tregouet David-Alexandre, Dörr Marcus, Meitinger Thomas, Lackner Karl J, Wolf Petra, Felix Stephan B, Landmesser Ulf, Costanzo Simona, Ziegler Andreas, Liu Yongmei, Völker Uwe, Palmas Walter, Prokisch Holger, Guo Xiuqing, Herder Christian, Blankenberg Stefan, Homuth Georg
Abstract excerpt
Hypertension represents a major cardiovascular risk factor. The pathophysiology of increased blood pressure (BP) is not yet completely understood. Transcriptome profiling offers possibilities to uncover genetics effects on BP. Based on 2 populations including 2549 individuals, a meta-analyses of monocytic transcriptome-wide profiles were performed to identify transcripts associated with BP. Replication was...
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