Article
Messenger RNA and MicroRNA transcriptomic signatures of cardiometabolic risk factors.
BMC genomics - 8 Feb 2017
McManus David D, Rong Jian, Huan Tianxiao, Lacey Sean, Tanriverdi Kahraman, Munson Peter J, Larson Martin G, Joehanes Roby, Murthy Venkatesh, Shah Ravi, Freedman Jane E, Levy Daniel
Abstract excerpt
BACKGROUND: Cardiometabolic (CM) risk factors are heritable and cluster in individuals. We hypothesized that CM risk factors are associated with multiple shared and unique mRNA and microRNA (miRNA) signatures. We examined associations of mRNA and miRNA levels with 6 CM traits: body mass index, HDL-cholesterol and triglycerides, fasting glucose, and systolic and diastolic blood pressures through cross-sectional...
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