Article
Association of the tandem polymorphisms (rs148314165, rs200820567) in TNFAIP3 with chronic hepatitis B virus infection in Chinese Han population.
Virology journal - 7 Aug 2017
Li Na, Shi Ying, Zhang Pingping, Sang Jiao, Li Fang, Deng Huan, Lv Yi, Han Qunying, Liu Zhengwen
Abstract excerpt
BACKGROUND: Chronic hepatitis B virus (HBV) infection remains an important public health issue. A20, a ubiquitin-editing protein encoded by tumor necrosis factor alpha-inducible protein 3 (TNFAIP3) gene, is complicated in HBV infection and liver injury. The tandem polymorphisms (rs148314165, rs200820567), deletion T followed by a T to A transversion and collectively referred to as TT > A in TNFAIP3, may attenuate...
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