Association between TNFAIP3 nonsynonymous single-nucleotide polymorphism rs2230926 and chronic hepatitis B virus infection in a Chinese Han population.

doi:10.1186/s12985-015-0268-6

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Article

Association between TNFAIP3 nonsynonymous single-nucleotide polymorphism rs2230926 and chronic hepatitis B virus infection in a Chinese Han population.

Virology journal - 28 Feb 2015

Zhang Pingping, Li Na, Zhu Qianqian, Li Fang, Yang Cuiling, Zeng Xiaoyan, Lv Yi, Zhou Zhihua, Han Qunying, Liu Zhengwen

Abstract excerpt

BACKGROUND: Single-nucleotide polymorphisms (SNPs) in tumor necrosis factor alpha-inducible protein 3 (TNFAIP3) gene have been linked to inflammatory, immunological and malignant diseases. Hepatitis B virus (HBV) infection is characterized by immunopathogenesis. This study investigated the association of rs2230926, a nonsynonymous SNP in TNFAIP3 gene, with chronic HBV infection. METHODS: Four hundred and...

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PMID: 25890346
DOI: 10.1186/s12985-015-0268-6
PMCID: PMC4359777

Genes

TNFAIP3

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