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Emergence of a colistin-resistant Escherichia coli clinical isolate harboring mcr-1 in Japan

2 Aug 2017

Abstract excerpt

The mcr-1 is a gene encoding a phosphoethanolamine transferase, which confers resistance to colistin by transferring phosphoethanolamine to lipid A. We describe here the emergence of a colistin-resistant Escherichia coli clinical isolate harboring plasmid-mediated mcr-1 in Japan. The isolate belonged to ST5702 and is suspected to come from livestock and transmitted to human. This is the first report of a clinical...

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PMID: 28780184
DOI: 10.1016/j.ijid.2017.07.023

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