Article
Diversified mcr-1-Harbouring Plasmid Reservoirs Confer Resistance to Colistin in Human Gut Microbiota.
mBio - 5 Apr 2016
Ye Huiyan, Li Yihui, Li Zhencui, Gao Rongsui, Zhang Han, Wen Ronghui, Gao George F, Hu Qinghua, Feng Youjun
Abstract excerpt
UNLABELLED: Colistin is an ultimate line of refuge against multidrug-resistant Gram-negative pathogens. Very recently, the emergence of plasmid-mediatedmcr-1colistin resistance has become a great challenge to global public health, raising the possibility that dissemination of themcr-1gene is underestimated and diversified. Here, we report three cases of plasmid-carried MCR-1 colistin resistance in isolates from...
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