Article
A clinical isolate of Escherichia coli co-harbouring mcr-1 and blaNDM-5 in Japan.
Journal of medical microbiology - 1 Aug 2018
Uchida Hiroki, Tada Tatsuya, Sugahara Yoshie, Kato Akira, Miyairi Isao, Kirikae Teruo
Abstract excerpt
The mcr-1 gene encodes a phosphoethanolamine transferase, which confers resistance to colistin by transferring phosphoethanolamine to lipid A. This study describes the emergence of a colistin- and carbapenem-resistant clinical isolate of Escherichia coli harbouring mcr-1 and blaNDM-5 genes, located on 90 and 150 Kb plasmids, respectively. The isolate belonged to ST132. This is the first report of a clinical...
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