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Article

Association between the Lynch syndrome gene MSH2 and breast cancer susceptibility in a Canadian familial cancer registry.

Journal of medical genetics - 1 Nov 2017

Goldberg Mira, Bell Kathleen, Aronson Melyssa, Semotiuk Kara, Pond Greg, Gallinger Steven, Zbuk Kevin

Abstract excerpt

BACKGROUND: Previous studies assessing breast cancer risk in families with Lynch syndrome (LS) have yielded conflicting results. Furthermore, conclusions are limited by small sample size and few breast cancer outcomes. This study assesses breast cancer risk in a large prospectively followed LS cohort. METHODS: Pedigrees of 325 unrelated families with LS within the Familial Gastrointestinal Cancer Registry in...

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Source

Identifiers

PMID: 28779004
DOI: 10.1136/jmedgenet-2017-104542

Genes

MSH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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