Article
Comprehensive Molecular Profiling of Olfactory Neuroblastoma Identifies Potentially Targetable <i>FGFR3</i> Amplifications
3 Aug 2017
Abstract excerpt
Abstract Olfactory neuroblastomas (ONBs), also known as esthesioneuroblastomas, are malignant round-cell tumors that represent up to 5% of sinonasal malignancies. Despite their aggressive course, molecular studies of ONBs have been limited, and targeted therapies are lacking. To identify potential oncogenic drivers and targetable pathways in ONBs, we characterized 20 ONBs, including archived ONBs profiled by...
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