Article
Comprehensive Genomic Profiling of Esthesioneuroblastoma Reveals Additional Treatment Options.
The oncologist - 1 Jul 2017
Gay Laurie M, Kim Sungeun, Fedorchak Kyle, Kundranda Madappa, Odia Yazmin, Nangia Chaitali, Battiste James, Colon-Otero Gerardo, Powell Steven, Russell Jeffery, Elvin Julia A, Vergilio Jo-Anne, Suh James, Ali Siraj M, Stephens Philip J, Miller Vincent A, Ross Jeffrey S
Abstract excerpt
BACKGROUND: Esthesioneuroblastoma (ENB), also known as olfactory neuroblastoma, is a rare malignant neoplasm of the olfactory mucosa. Despite surgical resection combined with radiotherapy and adjuvant chemotherapy, ENB often relapses with rapid progression. Current multimodality, nontargeted therapy for relapsed ENB is of limited clinical benefit. MATERIALS AND METHODS: We queried whether comprehensive genomic...
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