Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The microbial metabolite desaminotyrosine protects from influenza through type I interferon

3 Aug 2017

Abstract excerpt

Eat more plants for influenza resilience Antibiotic treatment worsens influenza in mice, possibly because the concomitant loss of the microbiota interrupts the production of bioactive metabolites. Steed et al. found that a microbial product, desaminotyrosine (DAT), produced by an obligate clostridial anaerobe from the digestion of plant flavonoids, is beneficial during influenza. DAT enters the bloodstream and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Clostridium difficile and Clostridium perfringens research
Share to Gut microbiota and health
Share to Immune Response and Inflammation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28774928
DOI: 10.1126/science.aam5336

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 9 closest

The microbial metabolite desaminotyrosine protects from influenza through type I interferonPMID 28774928Read ↗

A microbial metabolite protects against graft-versus-host disease via mTORC1 and STING-dependent intestinal regenerationSemantic proximity Read ↗

Supersulfides: A Promising Therapeutic Approach for Autoinflammatory DiseasesSemantic proximity Read ↗

mSphere of Influence: a Controlled Burn-Pathogen Manipulation of the Dynamic Chemistry That Results from Inflammation.Semantic proximity Read ↗

Host-directed antiviral therapeutics and the NIAID research agenda: an underexplored frontierSemantic proximity Read ↗

Metal-Protein Nanoparticles Facilitate Anti-VSV and H1N1 Viruses Through the Coordinative Actions on Innate Immune Responses and METTL14.Semantic proximity Read ↗

Hydroxytyrosol Recovers SARS-CoV-2-PLpro-Dependent Impairment of Interferon Related Genes in Polarized Human Airway, Intestinal and Liver Epithelial CellsSemantic proximity Read ↗

Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapySemantic proximity Read ↗

Effect of Combined Polyphenol on the Disease Course in Children Diagnosed with InfluenzaSemantic proximity Read ↗

Single-centre, randomised clinical trial of the immunomodulatory mechanisms of daily supplementation of palm tocotrienol-rich fraction in healthy human volunteers following influenza vaccinationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.