Article
Metal-Protein Nanoparticles Facilitate Anti-VSV and H1N1 Viruses Through the Coordinative Actions on Innate Immune Responses and METTL14.
Macromolecular bioscience - 1 Apr 2021
Zhu Xin-Jie, Feng Jin-Qiu, Zheng Meng-Zhu, Yang Ze-Ruo, Zhao Lei, Zhang Wei, Zhong Wu, Chen Ying-Yu, Lin Jian
Abstract excerpt
Host defense systems can invade viral infection through immune responses and cellular metabolism. Recently, many studies have shown that cellular metabolism can be reprogrammed through N6 -methyladenosine (m6 A) modifications during viral infection. Among of them, methyltransferase like-14 enzyme (METTL14) plays an important role in m6 A RNA modification, yet its antiviral function still remains unclear. In this...
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