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Article

A network-based gene expression signature informs prognosis and treatment for colorectal cancer patients.

PloS one - 1 Jan 2012

Shi Mingguang, Beauchamp R Daniel, Zhang Bing

Abstract excerpt

BACKGROUND: Several studies have reported gene expression signatures that predict recurrence risk in stage II and III colorectal cancer (CRC) patients with minimal gene membership overlap and undefined biological relevance. The goal of this study was to investigate biological themes underlying these signatures, to infer genes of potential mechanistic importance to the CRC recurrence phenotype and to test whether...

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PMID: 22844451
DOI: 10.1371/journal.pone.0041292
PMCID: PMC3402487

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