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Article

Exploration of predictive biomarkers for postoperative recurrence of stage II/III colorectal cancer using genomic sequencing.

Cancer medicine - 1 Sept 2022

Kishigami Fumishi, Tanaka Yosuke, Yamamoto Yoko, Ueno Toshihide, Kojima Shinya, Sato Kazuhito, Inoue Satoshi, Sugaya Saori, Ishihara Soichiro, Mano Hiroyuki, Kawazu Masahito

Abstract excerpt

Postoperative recurrence of colorectal cancer (CRC) eventually leads to therapeutic failure; therefore, treatment strategies based on accurate prediction of recurrence are urgently required. To identify biomarkers that can predict treatment outcomes, we compared the mutational profiles of surgically resected specimens from patients with recurrent cancer with those from patients with non-recurrent cancer. Target...

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PMID: 35343095
DOI: 10.1002/cam4.4710
PMCID: PMC9487878

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