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Avian influenza: genetic evolution under vaccination pressure

24 Jan 2008

Abstract excerpt

Antigenic drift of avian influenza viruses (AIVs) has been observed in chickens after extended vaccination program, similar to those observed with human influenza viruses. To evaluate the evolutionary properties of endemic AIV under high vaccination pressure (around 2 billion doses used in the last 12 years), we performed a pilot phylogenic analysis of the hemagglutinin (HA) gene of AIVs isolated from 1994 to...

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PMID: 18218105
DOI: 10.1186/1743-422x-5-15

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