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Article

Association of alpha A-crystallin polymorphisms with susceptibility to nuclear age-related cataract in a Han Chinese population.

BMC ophthalmology - 29 Jul 2017

Zhao Zhennan, Fan Qi, Zhou Peng, Ye HongFei, Cai Lei, Lu Yi

Abstract excerpt

BACKGROUND: Alpha A-crystallin (CRYAA) is considered critical for the maintenance of lens transparency and is related to the pathogenesis of age-related cataracts (ARCs), especially the nuclear subtype. As the 5' untranslated region (5' UTR) modulates gene expression, the purpose of current study was to investigate whether single nucleotide polymorphisms (SNPs) in the 5' UTR of CRYAA were associated with...

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Source

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Identifiers

PMID: 28755661
DOI: 10.1186/s12886-017-0529-9
PMCID: PMC5534246

Genes

CRYAA
ARC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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