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Article

TERT Promoter Hypermethylation in Gastrointestinal Cancer: A Potential Stool Biomarker

28 Jul 2017

Abstract excerpt

Abstract Background There is a high demand for noninvasive screening tools for gastrointestinal cancer (GIC) detection, and GIC-specific markers are required for such purposes. It is established that induction of the telomerase reverse transcriptase gene (TERT) coupled with telomerase activation is essential for cancer development/progression and aberrant TERT promoter methylation of specific 5′—C—phosphate—G—3′...

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PMID: 28754720
DOI: 10.1634/theoncologist.2017-0064

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