Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

IRX3 is a genetic modifier for birth weight, adolescent obesity and transaminase metabolism.

Pediatric obesity - 1 Mar 2018

Liu C, Chu C, Zhang J, Wu D, Xu D, Li P, Chen Y, Liu B, Pei L, Zhang L, Liu S, Qi T, Lou X-Y, Li L

Abstract excerpt

OBJECTIVE: IRX3 expression has been functionally associated in obesity-associated long-distance susceptibility loci, but the effect of the IRX3 genetic variants on human obesity and obesity-related metabolism remains uncertain. METHODS: To determine the genetic role of IRX3, we conducted a molecular epidemiological analysis using three haplotype tagging single nucleotide polymorphisms (SNPs; rs8053360, rs3751723...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Alanine Transaminase

Share to Aspartate Aminotransferases

Share to Birth Weight

Share to Body Mass Index

Share to Diabetes Mellitus

Share to Homeodomain Proteins

Share to Metabolic Syndrome

Share to Pediatric Obesity

Source

Identifiers

PMID: 28316138
DOI: 10.1111/ijpo.12214

Genes

IRX3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

IRX3 is a genetic modifier for birth weight, adolescent obesity and transaminase metabolism.PMID 28316138Read ↗

Associations between KCNQ1 and ITIH4 gene polymorphisms and infant weight gain in early life.Semantic proximity Read ↗

Interaction analysis of FTO and IRX3 genes with obesity and related metabolic disorders in an admixed Latin American population: a possible risk increases of body weight excessSemantic proximity Read ↗

[Association of abnormal lipid metabolism with INSIG2 gene variant in overweight and obese children].Semantic proximity Read ↗

Genetic susceptibility, birth weight and obesity risk in young Chinese.Semantic proximity Read ↗

The combination of genetic variations in the PRDX3 gene and dietary fat intake contribute to obesity risk.Semantic proximity Read ↗

The Born in Guangzhou Cohort Study enables generational genetic discoveries.Semantic proximity Read ↗

FTO Obesity Risk Variants Are Linked to Adipocyte IRX3 Expression and BMI of Children - Relevance of FTO Variants to Defend Body Weight in Lean Children?Semantic proximity Read ↗

IRX3 Promotes the Browning of White Adipocytes and Its Rare Variants are Associated with Human Obesity Risk.Semantic proximity Read ↗

Regulations of Adipocyte Phenotype and Obesity by IRX3. Positive or Negative?Semantic proximity Read ↗

Interaction between obesity and the Hypoxia Inducible Factor 3 Alpha Subunit rs3826795 polymorphism in relation with plasma alanine aminotransferase.Semantic proximity Read ↗

Associations between Gene-Gene Interaction and Overweight/Obesity of 12-Month-Old Chinese Infants.Semantic proximity Read ↗

The birth weight lowering C-allele of rs900400 near LEKR1 and CCNL1 associates with elevated insulin release following an oral glucose challenge.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.