Exome sequencing identifies recurrent BCOR alterations and the absence of KLF2, TNFAIP3 and MYD88 mutations in splenic diffuse red pulp small B-cell lymphoma.

doi:10.3324/haematol.2016.160192

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Article

Exome sequencing identifies recurrent BCOR alterations and the absence of KLF2, TNFAIP3 and MYD88 mutations in splenic diffuse red pulp small B-cell lymphoma.

Haematologica - 1 Oct 2017

Jallades Laurent, Baseggio Lucile, Sujobert Pierre, Huet Sarah, Chabane Kaddour, Callet-Bauchu Evelyne, Verney Aurélie, Hayette Sandrine, Desvignes Jean-Pierre, Salgado David, Levy Nicolas, Béroud Christophe, Felman Pascale, Berger Françoise, Magaud Jean-Pierre, Genestier Laurent, Salles Gilles, Traverse-Glehen Alexandra

Abstract excerpt

Splenic diffuse red pulp lymphoma is an indolent small B-cell lymphoma recognized as a provisional entity in the World Health Organization 2008 classification. Its precise relationship to other related splenic B-cell lymphomas with frequent leukemic involvement or other lymphoproliferative disorders remains undetermined. We performed whole-exome sequencing to explore the genetic landscape of ten cases of splenic...

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Identifiers

PMID: 28751561
DOI: 10.3324/haematol.2016.160192
PMCID: PMC5622860

Genes

KLF2
MYD88
TNFAIP3
BCOR
BCL6

Provenance

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