Article
High-levels of acquired drug resistance in adult patients failing first-line antiretroviral therapy in a rural HIV treatment programme in KwaZulu-Natal, South Africa.
PloS one - 1 Jan 2013
Manasa Justen, Lessells Richard J, Skingsley Andrew, Naidu Kevindra K, Newell Marie-Louise, McGrath Nuala, de Oliveira Tulio
Abstract excerpt
OBJECTIVE: To determine the frequency and patterns of acquired antiretroviral drug resistance in a rural primary health care programme in South Africa. DESIGN: Cross-sectional study nested within HIV treatment programme. METHODS: Adult (≥ 18 years) HIV-infected individuals initially treated with a first-line stavudine- or zidovudine-based antiretroviral therapy (ART) regimen and with evidence of virological...
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