Article
A Novel Mutant Allele of Pw1/Peg3 Does Not Affect Maternal Behavior or Nursing Behavior.
PLoS genetics - 1 May 2016
Denizot Anne-Lyse, Besson Vanessa, Correra Rosa Maria, Mazzola Alessia, Lopes Izolina, Courbard Jean-Remy, Marazzi Giovanna, Sassoon David A
Abstract excerpt
Parental imprinting is a mammalian-specific form of epigenetic regulation in which one allele of a gene is silenced depending on its parental origin. Parentally imprinted genes have been shown to play a role in growth, metabolism, cancer, and behavior. Although the molecular mechanisms underlying parental imprinting have been largely elucidated, the selective advantage of silencing one allele remains unclear. The...
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