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Article

Genome-wide association analysis for lethal brachycephalic-like facial dysmorphia in Labrador Retrievers.

Animal genetics - 1 Feb 2020

Vasiliadis D, Dierks C, Hoffmann H, Hellige M, Hewicker-Trautwein M, Metzger J, Distl O

Abstract excerpt

A GWAS was performed for inborn X-linked facial dysmorphia with severe growth retardation in Labrador Retrievers. This lethal condition was mapped on the X chromosome at 17-21 Mb and supported by eight SNPs in complete LD. Dams of affected male puppies were heterozygous for the significantly associated SNPs and male affected puppies carried the associated alleles hemizygously. In the near vicinity to the...

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Identifiers

PMID: 31691328
DOI: 10.1111/age.12875

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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