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Article

Analysis of SDHAF3 in familial and sporadic pheochromocytoma and paraganglioma.

BMC cancer - 24 Jul 2017

Dwight Trisha, Na Un, Kim Edward, Zhu Ying, Richardson Anne Louise, Robinson Bruce G, Tucker Katherine M, Gill Anthony J, Benn Diana E, Clifton-Bligh Roderick J, Winge Dennis R

Abstract excerpt

BACKGROUND: Germline mutations in genes encoding subunits of succinate dehydrogenase (SDH) are associated with the development of pheochromocytoma (PC) and/or paraganglioma (PGL). As assembly factors have been identified as playing a role in maturation of individual SDH subunits and assembly of the functioning SDH complex, we hypothesized that SDHAF3 variants may be associated with PC/PGL and functionality of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 28738844
DOI: 10.1186/s12885-017-3486-z
PMCID: PMC5525311

Genes

SDHAF3
SDHB

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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