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Article

Structural and functional consequences of succinate dehydrogenase subunit B mutations.

Endocrine-related cancer - 1 Jun 2015

Kim E, Rath E M, Tsang V H M, Duff A P, Robinson B G, Church W B, Benn D E, Dwight T, Clifton-Bligh R J

Abstract excerpt

Mitochondrial dysfunction, due to mutations of the gene encoding succinate dehydrogenase (SDH), has been implicated in the development of adrenal phaeochromocytomas, sympathetic and parasympathetic paragangliomas, renal cell carcinomas, gastrointestinal stromal tumours and more recently pituitary...

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Source

Identifiers

PMID: 25972245
DOI: 10.1530/ERC-15-0099

Genes

SDHB

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25972245-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Structural and functional consequences of succinate dehydrogenase subunit B mutations.PMID 25972245Read ↗

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