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Bone morphogenetic proteins, breast cancer, and bone metastases: striking the right balance

21 Jul 2017

Abstract excerpt

Bone morphogenetic proteins (BMPs) belong to the TGF-β super family, and are essential for the regulation of foetal development, tissue differentiation and homeostasis and a multitude of cellular functions. Naturally, this has led to the exploration of aberrance in this highly regulated system as a key factor in tumourigenesis. Originally identified for their role in osteogenesis and bone turnover, attention has...

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PMID: 28733469
DOI: 10.1530/erc-17-0139

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