Article
The role of a FADS1 polymorphism in the association of fatty acid blood levels, BMI and blood pressure in young children-Analyses based on path models.
PloS one - 1 Jan 2017
Wolters Maike, Dering Carmen, Siani Alfonso, Russo Paola, Kaprio Jaakko, Risé Patrizia, Moreno Luis A, De Henauw Stefaan, Mehlig Kirsten, Veidebaum Toomas, Molnár Denés, Tornaritis Michael, Iacoviello Licia, Pitsiladis Yannis, Galli Claudio, Foraita Ronja, Börnhorst Claudia
Abstract excerpt
BACKGROUND: The recent obesity epidemic in children also showed an increase in the prevalence of hypertension. As blood pressure (BP) is associated with (long-chain) polyunsaturated fatty acids (LC PUFA), genetic variation in desaturase enzymes being involved in the synthesis of LC PUFA may be associated with BP. This study aimed to investigate the direct effects (independent of mediating variables) and indirect...
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