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Population dynamics of engineered underdominance and killer-rescue gene drives in the control of disease vectors

23 Mar 2018

Abstract excerpt

A number of different genetics-based vector control methods have been proposed. Two approaches currently under development in Aedes aegypti mosquitoes are the two-locus engineered underdominance and killer-rescue gene drive systems. Each of these is theoretically capable of increasing in frequency within a population, thus spreading associated desirable genetic traits. Thus they have gained attention for their...

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PMID: 29570717
DOI: 10.1371/journal.pcbi.1006059

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