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Clinical study of genomic drivers in pancreatic ductal adenocarcinoma

18 Jul 2017

Abstract excerpt

BACKGROUND: Pancreatic ductal adenocarcinoma (PDA) is a lethal cancer with complex genomes and dense fibrotic stroma. This study was designed to identify clinically relevant somatic aberrations in pancreatic cancer genomes of patients with primary and metastatic disease enrolled and treated in two clinical trials. METHODS: Tumour nuclei were flow sorted prior to whole genome copy number variant (CNV) analysis....

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Share to Cancer Genomics and Diagnostics
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PMID: 28720843
DOI: 10.1038/bjc.2017.209

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