Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of polymorphisms and reduced expression levels of the NR4A2 gene with Parkinson's disease in a Mexican population.

Journal of the neurological sciences - 15 Aug 2017

Ruiz-Sánchez Elizabeth, Yescas Petra, Rodríguez-Violante Mayela, Martínez-Rodríguez Nancy, Díaz-López Jesica N, Ochoa Adriana, Valdes-Rojas Sergio S, Magos-Rodríguez Daniel, Rojas-Castañeda Julio C, Cervantes-Arriaga Amin, Canizales-Quinteros Samuel, Rojas Patricia

Abstract excerpt

INTRODUCTION: The NR4A2 transcription factor is important in the development, survival and phenotype of dopaminergic neurons and it is postulated as a possible biomarker for Parkinson's disease (PD). Therefore, our aim was to analyze in a sample of a Mexican population with idiopathic PD, mutations (in two hotspot mutation regions) and two polymorphisms (rs34884856 in promotor and rs35479735 intronic regions) of...

Read the complete abstract on PubMed

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cohort Studies
Share to Gene Expression
Share to Genetic Association Studies
Share to Mexico
Share to Nuclear Receptor Subfamily 4, Group A, Member 2
Share to Parkinson Disease
Share to Population Surveillance
Share to RNA, Messenger

Source

Identifiers

PMID: 28716280
DOI: 10.1016/j.jns.2017.05.029

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of polymorphisms and reduced expression levels of the NR4A2 gene with Parkinson's disease in a Mexican population.PMID 28716280Read ↗

Genetic analysis of NR4A2 gene in a large population of Han Chinese patients with Parkinson's disease.Semantic proximity Read ↗

NR4A2 genetic variation and Parkinson's disease: Evidence from a systematic review and meta-analysis.Semantic proximity Read ↗

Characterisation of a novel NR4A2 mutation in Parkinson's disease brain.Semantic proximity Read ↗

Mutations in NR4A2 associated with familial Parkinson disease.Semantic proximity Read ↗

Extended mutation analysis and association studies of Nurr1 (NR4A2) in Parkinson disease.Semantic proximity Read ↗

Identification and characterization of human NR4A2 polymorphisms in attention deficit hyperactivity disorder.Semantic proximity Read ↗

Loss-of-Function Mutations in NR4A2 Cause Dopa-Responsive Dystonia Parkinsonism.Semantic proximity Read ↗

Genetic variations of NR2A1 in Asian populations: implications in pharmacogenetics studies.Semantic proximity Read ↗

On the Role of Adenosine A2A Receptor Gene Transcriptional Regulation in Parkinson’s DiseaseSemantic proximity Read ↗

Association between CHRNA5 polymorphisms and Parkinson's disease in Northern Chinese Han population: a case-control study.Semantic proximity Read ↗

Detection of copy number changes in genes associated with Parkinson's disease in Iranian patientsSemantic proximity Read ↗

Assessment of RIT2 rs12456492 association with Parkinson's disease in Mainland China.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.