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Plasmodium knowlesi:a superbin vivononhuman primate model of antigenic variation in malaria

17 Jul 2017

Abstract excerpt

Antigenic variation in malaria was discovered in Plasmodium knowlesi studies involving longitudinal infections of rhesus macaques (M. mulatta). The variant proteins, known as the P. knowlesi Schizont Infected Cell Agglutination (SICA) antigens and the P. falciparum Erythrocyte Membrane Protein 1 (PfEMP1) antigens, expressed by the SICAvar and var multigene families, respectively, have been studied for over 30...

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PMID: 28712361
DOI: 10.1017/s0031182017001135

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