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Plasmodium knowlesi gene expression differs in ex vivo compared to in vitro blood-stage cultures

12 Mar 2015

Abstract excerpt

BACKGROUND: Plasmodium knowlesi is one of five Plasmodium species known to cause malaria in humans and can result in severe illness and death. While a zoonosis in humans, this simian malaria parasite species infects macaque monkeys and serves as an experimental model for in vivo, ex vivo and in vitro studies. It has underpinned malaria discoveries relating to host-pathogen interactions, the immune response and...

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PMID: 25880967
DOI: 10.1186/s12936-015-0612-8

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