Article
C. elegans SMA-10 regulates BMP receptor trafficking.
PloS one - 1 Jan 2017
Gleason Ryan J, Vora Mehul, Li Ying, Kane Nanci S, Liao Kelvin, Padgett Richard W
Abstract excerpt
Signal transduction of the conserved transforming growth factor-β (TGFβ) family signaling pathway functions through two distinct serine/threonine transmembrane receptors, the type I and type II receptors. Endocytosis orchestrates the assembly of signaling complexes by coordinating the entry of receptors with their downstream signaling mediators. Recently, we showed that the C. elegans type I bone morphogenetic...
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