Article
KIF17 maintains the epithelial phenotype of breast cancer cells and curbs tumour metastasis.
Cancer letters - 1 Nov 2022
Li Tianfu, Zhai Duanyang, Zhang Mengmeng, Ye Runyi, Kuang Xiaying, Shao Nan, Bi Jiong, Lin Ying
Abstract excerpt
Kinesin superfamily motor protein 17 (KIF17) was previously identified downregulated in breast cancer and correlated with patient prognosis. However, its pathophysiological role in tumours remains unknown. Here, we confirmed that KIF17 was significantly under-expressed in breast cancer tissues and low KIF17 expression correlated with poor outcomes in patients with breast cancer. In vitro and in vivo experiments...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.