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Article

Cigarette smoke differentially affects IL-13-induced gene expression in human airway epithelial cells

1 Jul 2017

Abstract excerpt

Allergic airways inflammation in asthma is characterized by an airway epithelial gene signature composed of POSTN, CLCA1, and SERPINB2. This Th2 gene signature is proposed as a tool to classify patients with asthma into Th2-high and Th2-low phenotypes. However, many asthmatics smoke and the effects of cigarette smoke exposure on the epithelial Th2 gene signature are largely unknown. Therefore, we investigated the...

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Identifiers

PMID: 28701525
DOI: 10.14814/phy2.13347

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