Article
Cost Effectiveness of Risk-Reducing Mastectomy versus Surveillance in BRCA Mutation Carriers with a History of Ovarian Cancer.
Annals of surgical oncology - 1 Oct 2017
Gamble Charlotte, Havrilesky Laura J, Myers Evan R, Chino Junzo P, Hollenbeck Scott, Plichta Jennifer K, Kelly Marcom P, Shelley Hwang E, Kauff Noah D, Greenup Rachel A
Abstract excerpt
BACKGROUND: The appropriate management of breast cancer risk in BRCA mutation carriers following ovarian cancer diagnosis remains unclear. We sought to determine the survival benefit and cost effectiveness of risk-reducing mastectomy (RRM) among women with BRCA1/2 mutations following stage II-IV ovarian cancer. DESIGN: We constructed a decision model from a third-party payer perspective to compare annual...
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