Article
Ganglioside glycosyltransferases are S-acylated at conserved cysteine residues involved in homodimerisation.
The Biochemical journal - 7 Aug 2017
Chumpen Ramirez Sabrina, Ruggiero Fernando M, Daniotti Jose Luis, Valdez Taubas Javier
Abstract excerpt
Ganglioside glycosyltransferases (GGTs) are type II membrane proteins bearing a short N-terminal cytoplasmic tail, a transmembrane domain (TMD), and a lumenal catalytic domain. The expression and activity of these enzymes largely determine the quality of the glycolipids that decorate mammalian cell membranes. Many glycosyltransferases (GTs) are themselves glycosylated, and this is important for their proper...
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