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Article

Axon guidance pathways served as common targets for human speech/language evolution and related disorders.

Brain and language - 1 Nov 2017

Lei Huimeng, Yan Zhangming, Sun Xiaohong, Zhang Yue, Wang Jianhong, Ma Caihong, Xu Qunyuan, Wang Rui, Jarvis Erich D, Sun Zhirong

Abstract excerpt

Human and several nonhuman species share the rare ability of modifying acoustic and/or syntactic features of sounds produced, i.e. vocal learning, which is the important neurobiological and behavioral substrate of human speech/language. This convergent trait was suggested to be associated with significant genomic convergence and best manifested at the ROBO-SLIT axon guidance pathway. Here we verified the...

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Identifiers

PMID: 28692932
DOI: 10.1016/j.bandl.2017.06.007

Genes

PRAME
FOXP2

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