Article
Epigenome-wide association of PTSD from heterogeneous cohorts with a common multi-site analysis pipeline.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Sept 2017
Ratanatharathorn Andrew, Boks Marco P, Maihofer Adam X, Aiello Allison E, Amstadter Ananda B, Ashley-Koch Allison E, Baker Dewleen G, Beckham Jean C, Bromet Evelyn, Dennis Michelle, Garrett Melanie E, Geuze Elbert, Guffanti Guia, Hauser Michael A, Kilaru Varun, Kimbrel Nathan A, Koenen Karestan C, Kuan Pei-Fen, Logue Mark W, Luft Benjamin J, Miller Mark W, Mitchell Colter, Nugent Nicole R, Ressler Kerry J, Rutten Bart P F, Stein Murray B, Vermetten Eric, Vinkers Christiaan H, Youssef Nagy A, Uddin Monica, Nievergelt Caroline M, Smith Alicia K
Abstract excerpt
Compelling evidence suggests that epigenetic mechanisms such as DNA methylation play a role in stress regulation and in the etiologic basis of stress related disorders such as Post traumatic Stress Disorder (PTSD). Here we describe the purpose and methods of an international consortium that was developed to study the role of epigenetics in PTSD. Inspired by the approach used in the Psychiatric Genomics...
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