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Article

Impaired salivary gland activity in patients with autoimmune polyendocrine syndrome type I.

Autoimmunity - 1 Jun 2017

Oftedal Bergithe E, Marthinussen Mihaela Cuida, Erichsen Martina M, Tveitarås Maria K, Kjellesvik-Kristiansen Anja, Hammenfors Daniel, Jonsson Malin V, Kisand Kai, Jonsson Roland, Wolff Anette S B

Abstract excerpt

Autoimmune polyendocrine syndrome type I (APS-I) is a severe disease caused by mutations in the autoimmune regulator (AIRE) gene. We hypothesized that salivary gland dysfunction could be a possible unexplored component of these patients and here aimed to investigate salivary and lachrymal symptoms in the Norwegian cohort of APS-I patients (N = 41) and the aetiology behind it. Sicca symptoms and possible...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28686485
DOI: 10.1080/08916934.2017.1344972

Genes

AIRE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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