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Article

Autoimmunity and cystatin SA1 deficiency behind chronic mucocutaneous candidiasis in autoimmune polyendocrine syndrome type 1.

Journal of autoimmunity - 1 May 2013

Lindh Emma, Brännström Johan, Jones Petra, Wermeling Fredrik, Hässler Signe, Betterle Corrado, Garty Ben Zion, Stridsberg Mats, Herrmann Björn, Karlsson Mikael C I, Winqvist Ola

Abstract excerpt

Patients with the monogenic disease autoimmune polyendocrine syndrome type I (APSI) develop autoimmunity against multiple endocrine organs and suffer from chronic mucocutaneous candidiasis (CMC), a paradoxical complication with an unknown mechanism. We report here that saliva from APSI patients with CMC is defective in inhibiting growth of Candida albicans in vitro and show reduced levels of a salivary protein...

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Identifiers

PMID: 23122533
DOI: 10.1016/j.jaut.2012.10.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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