Article
Caerulomycin A suppresses the differentiation of naïve T cells and alleviates the symptoms of experimental autoimmune encephalomyelitis.
Autoimmunity - 1 Aug 2017
Kujur Weshely, Gurram Rama Krishna, Maurya Sudeep K, Nadeem Sajid, Chodisetti Sathi Babu, Khan Nargis, Agrewala Javed Naim
Abstract excerpt
Multiple sclerosis (MS) is a highly detrimental autoimmune disease of the central nervous system. There is no cure for it but the treatment typically focuses on subsiding severity and recurrence of the disease. Experimental autoimmune encephalomyelitis (EAE) is an animal model of MS. It is characterized by frequent relapses due to the generation of memory T cells. Caerulomycin A (CaeA) is known to suppress the...
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