Article
Osteopontin polymorphism increases gastric precancerous intestinal metaplasia susceptibility in Helicobacter pylori infected male.
Future oncology (London, England) - 1 Jul 2017
Chang Wei-Lun, Lin Meng-Ying, Kuo Hsin-Yu, Yang Hsiao-Bai, Cheng Hsiu-Chi, Lu Cheng-Chan, Sheu Bor-Shyang
Abstract excerpt
AIM: Whether genetic polymorphisms of osteopontin (OPN) coding gene, SPP1, determine the risk of gastric precancerous intestinal metaplasia (IM) in Helicobacter pylori infected patients. PATIENTS & METHODS: Helicobacter pylori infected patients (100 with and 210 without IM) were recruited to evaluate the associations of SPP1 promoter polymorphisms with gastric IM and adjusted for age, sex and smoking. Gastric OPN...
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