Article
Risk prediction of gastric cancer by analysis of aberrant DNA methylation in non-neoplastic gastric epithelium.
Digestion - 1 Jan 2007
Tahara Tomomitsu, Arisawa Tomiyasu, Shibata Tomoyuki, Wang Fang Yu, Nakamura Masakatsu, Sakata Mikijyu, Nagasaka Mitsuo, Takagi Tamaki, Kamiya Yoshio, Fujita Hiroshi, Nakamura Masahiko, Hasegawa Shin, Iwata Masami, Takahama Kazuya, Watanabe Makoto, Hirata Ichiro, Nakano Hiroshi
Abstract excerpt
BACKGROUND: Aberrant DNA methylation is one of the major events in carcinogenesis. Promoter DNA methylation is also present in various non-neoplastic tissues including gastric epithelium as age-related phenomenon, suggesting that it occurs early in the process of tumorigenesis. AIM: We aimed to c...
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