Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cervical cancer stem cells manifest radioresistance: Association with upregulated AP-1 activity

30 Jun 2017

Abstract excerpt

Transcription factor AP-1 plays a central role in HPV-mediated cervical carcinogenesis. AP-1 has also been implicated in chemo-radio-resistance but the mechanism(s) remained unexplored. In the present study, cervical cancer stem-like cells (CaCxSLCs) isolated and enriched from cervical cancer cell lines SiHa and C33a demonstrated an elevated AP-1 DNA-binding activity in comparison to non-stem cervical cancer...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to FOXO transcription factor regulation
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28684765
DOI: 10.1038/s41598-017-05162-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cervical cancer stem cells manifest radioresistance: Association with upregulated AP-1 activityPMID 28684765Read ↗

ALDH-1-positive cells exhibited a radioresistant phenotype that was enhanced with hypoxia in cervical cancer.Semantic proximity Read ↗

Cervical cancer stem cell‑associated genes: Prognostic implications in cervical cancer (Review)Semantic proximity Read ↗

Cancer-initiating cells derived from established cervical cell lines exhibit stem-cell markers and increased radioresistanceSemantic proximity Read ↗

Expression and Functional Role of ALDH1 in Cervical Carcinoma CellsSemantic proximity Read ↗

Fra-1 Inhibits Cell Growth and the Warburg Effect in Cervical Cancer Cells via STAT1 Regulation of the p53 Signaling PathwaySemantic proximity Read ↗

Human Papillomavirus Infections and Cancer Stem Cells of Tumors from the Uterine CervixSemantic proximity Read ↗

Fra-1 is downregulated in cervical cancer tissues and promotes cervical cancer cell apoptosis by p53 signaling pathway in vitroSemantic proximity Read ↗

Low P16INK4A Expression Associated with High Expression of Cancer Stem Cell Markers Predicts Poor Prognosis in Cervical Cancer after RadiotherapySemantic proximity Read ↗

Characterization of cervical cancer stem cell-like cells: phenotyping, stemness, and human papilloma virus co-receptor expression.Semantic proximity Read ↗

Radiosensitivity of cervical cancer cell lines: the impact of polymorphisms in DNA repair genes.Semantic proximity Read ↗

AP-1-Dependent miR-21 Expression Contributes to Chemoresistance in Cancer Stem Cell-Like SP CellsSemantic proximity Read ↗

Quiescence and attenuated DNA damage response promote survival of esophageal cancer stem cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.