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Article

Cancer-initiating cells derived from established cervical cell lines exhibit stem-cell markers and increased radioresistance

28 Jan 2012

Abstract excerpt

BACKGROUND: Cancer-initiating cells (CICs) are proposed to be responsible for the generation of metastasis and resistance to therapy. Accumulating evidences indicates CICs are found among different human cancers and cell lines derived from them. Few studies address the characteristics of CICs in cervical cancer. We identify biological features of CICs from four of the best-know human cell lines from uterine...

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PMID: 22284662
DOI: 10.1186/1471-2407-12-48

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