Article
Effect of steroid hormone receptor gene variants PROGINS (Alu insertion) and PGR C/T (rs1042839) as a risk factor for recurrent pregnancy loss in Kashmiri population (North India).
The journal of obstetrics and gynaecology research - 1 Dec 2021
Khan Nebela, Zargar Mahrukh Hameed, Ahmed Rehana, Godha Meena, Ahmad Abida, Afroze Dil, Masoodi Shariq R
Abstract excerpt
AIM: To unveil and evaluate the association and analyze the incidence and pattern of PGR gene polymorphisms (PROGINS insertion and PGR exon 5-C/T polymorphism) in recurrent pregnancy loss (RPL) couples of Kashmir. METHODS: In this study, analyses of PGR gene polymorphisms in RPL couples were genotyped by amplification-refractory mutation system polymerase chain reaction (PCR) and PCR-restriction fragment length...
Topics
- Abortion, Habitual
- Case-Control Studies
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Hormones
- Humans
- India
- Polymorphism, Single Nucleotide