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Article

A proportion of patients with lymphoma may harbor mutations of the perforin gene.

Blood - 1 Jun 2005

Clementi Rita, Locatelli Franco, Dupré Loïc, Garaventa Alberto, Emmi Lorenzo, Bregni Marco, Cefalo Graziella, Moretta Antonia, Danesino Cesare, Comis Margherita, Pession Andrea, Ramenghi Ugo, Maccario Rita, Aricò Maurizio, Roncarolo Maria Grazia

Abstract excerpt

Perforin mutations have been demonstrated in a proportion of patients diagnosed with the familial form of hemophagocytic lymphohistiocytosis (HLH). In the present study, we evaluated whether some patients with lymphoma sharing clinical characteristics with HLH might harbor mutations of the perfor...

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Source

Identifiers

PMID: 15728124
DOI: 10.1182/blood-2004-04-1477

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-15728124-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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