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Article

Selection for long and short sleep duration in Drosophila melanogaster reveals the complex genetic network underlying natural variation in sleep.

PLoS genetics - 1 Dec 2017

Harbison Susan T, Serrano Negron Yazmin L, Hansen Nancy F, Lobell Amanda S

Abstract excerpt

Why do some individuals need more sleep than others? Forward mutagenesis screens in flies using engineered mutations have established a clear genetic component to sleep duration, revealing mutants that convey very long or short sleep. Whether such extreme long or short sleep could exist in natural populations was unknown. We applied artificial selection for high and low night sleep duration to an outbred...

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Identifiers

PMID: 29240764
DOI: 10.1371/journal.pgen.1007098
PMCID: PMC5730107

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EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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